Searchable abstracts of presentations at key conferences in endocrinology

ea0063p739 | Pituitary and Neuroendocrinology 2 | ECE2019

Investigation of the role of miR-126-3p in pituitary insufficiency following traumatic brain injury

Tufan Esra , Taheri Serpil , Karaca Zuleyha , Bayramov Kezban Korkmaz , Unluhizarci Kursad , Kelestimur Fahrettin

Aim: Traumatic brain injury (TBI) is known to be associated with pituitary insufficiency (PI). We have recently shown that there was a relationship between miR-126-3p, miR-3610 and PI developing in follow up of patients with TBI. In this study, we aimed to test the effects of miR-126-3p on hypothalamus pituitary-adrenal (HPA) and Growth hormone-Insulin like growth factor (GH-IGF-1) axes.Materials and methods: miR126-3p microinjection was performed to mou...